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Common dye turns skin invisible to see the organs inside

A non-toxic dye typically used in packaged foods has the potential to render the skin transparent, allowing view of underlying organs, according to researchers.

Scientists discovered that by applying a dye to the skin, they could visualise the veins supplying blood to the brain and observe the workings of organs and muscles beneath the surface of the skin.

The researchers carried out their investigation on mice, although they believe that the dye is safe in other animal types and, conceivably, even for human use.

The colourant in question is a food dye known as tartrazine, which is used for its yellowish hue. This very same colour, however, also enables it to absorb light, particularly blue and ultraviolet light.

We normally can't see through skin because of the way it scatters light, much like fog does, but the product takes advantage of skin's properties to stop it scattering light as much, making it seem more transparent.

Researchers can easily apply the dye by rubbing a solution of the colouring on to the animal's skin with water. After a few minutes, it wouldn't be visible to the naked eye, as it would have permeated into the skin.

Scientists were later able to observe the blood vessels and internal organs in the mice, as well as the muscle movements that occur as the digestive system operates.

After the trials, the dye will be removed with a wash, and its effects will be fully reversed. Any remaining dye in the skin will be absorbed and then pass out of the body in the urine.

The dye itself poses no risk to living organisms - which is fortunate, as it is utilised in confectionery, snack crisps and other edible items. The dye has already received certification from the US Food and Drug Administration, confirming it is safe for use in food.

It is unclear whether the process would be effective on humans, given the considerable thickness of their skin, which is approximately ten times that of a mouse. It may be feasible to use more dye or find a different method of delivery to ensure the substance penetrates the skin in this instance, researchers have proposed.

We might also be able to provide medical professionals with some assistance as they attempt to comprehend what is going on inside a patient’s body by doing that.

In medical science, we currently employ ultrasound technology to examine internal body structures," Ou said. "Unfortunately, many diagnostic systems are very costly and not readily available to a wide range of people, whereas our technology-based platforms should not be so.

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